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Yellapragada Subbarow

येल्लाप्रगड सुब्बाराव
1895 – 1948
MedicineChemistry

ATP, folic acid and the cancer drug methotrexate

Story

Dr. Y. Subbarow worked in the United States, where his research helped reveal the role of ATP as the energy molecule of cells. He led the development of folic acid synthesis, the anti-cancer drug methotrexate and the antibiotic aureomycin.

Key contributions

  • Fiske–Subbarow method for measuring phosphorus; role of ATP in muscle
  • Synthesis of folic acid and development of methotrexate
  • Led the discovery of aureomycin, the first tetracycline antibiotic

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